The support offered by Transnational Access comprises wet-lab and/or large-scale genomics data analysis. Costs of external user projects for consumables and for personnel required at the facilities will be fully covered by EASI-Genomics.
EASI-Genomics invites external users to apply for access by opening several calls for proposals. Interested users can submit proposals online using EASI-Genomics’ website. Proposals will be evaluated for scientific quality and impact, as well as eligibility and feasibility. EASI-Genomics recommends external users to contact the facilities offering the services of interest in order to discuss the feasibility of the submitted project prior to the submission of proposal. EASI-Genomics will launch four calls for proposal with a total budget of 6 million € (guidance average 40,000 per project).
Proposals will be handled confidentially.
Topics of the 1st Call for proposal:
- Sequencing of ancient DNA. Amongst others, applicants shall explicitly describe the status of immediately available sample material, and wet-lab and/or computational procedures required for support.
- Microbiome analyses of population-based and disease cohorts. Applicants shall explicitly describe the scientific value and quality control of the sample cohort(s). Wet-lab and/or computational procedures required for support shall be specified.
- Single-cell genomics. Amongst others, applicants shall describe what samples are available at EASI-Genomics facilities. Procedures required for wet lab and/or for data analysis support shall be clearly described.
- Identification of epigenetic signatures in human disease. Studies with samples derived from blood or analysing surrogate epigenetic markers are not eligible. Applicants shall instead focus on specific tissues/cell types to decipher epigenetic signatures with mechanistic relevance to disease. Applicants must specify available samples. Procedures required for wet lab and/or for data analysis support shall be clearly described.
- DNA and chromatin alterations: Applicants shall focus on mechanistically studying DNA and chromatin architecture alterations relevant to disease. For example, this can include analysis of the effect of structural variation or other functional analyses. Applicants shall explicitly describe the relevance of immediately available sample material required for disease-relevant and mechanistic analyses. Applicants shall specify wet-lab and/or computational procedures required for support.
- Sequence analysis of species of ecological and economic relevance using de novo sequence assembly and annotation. Applicants shall describe available samples including their economical relevance, and procedures required for wet lab and data analysis support.
- Data analysis. EASI-Genomics can provide data analysis for already existing data sets. Applicants should describe available data including sequencing technology used to generate it and the objective of the analysis. EASI-Genomics will provide state of the art bioinformatics support.